About 1 result found for searched term "PS315 " (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27968 | PS315 | PKC |
| PS315, a derivative of PS48, is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing a displacement of the active site residue Lys111. PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM). PS315 has anti-cancer activity. | ||
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