About 3 results found for searched term "PROTAC BTK Degrader-3" (0.378 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43440 | PROTAC BTK Degrader-3 | PROTAC |
| PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. | ||
| M43406 | PROTAC BTK Degrader-6 | BTK |
| PROTAC BTK Degrader-6 is a PROTAC BTK degrader (DC50: 3.18 nM. | ||
| M58639 | Propargyl-PEG1-acid | PROTAC Linker |
| 3-(2-Propynyloxy)propanoic acid | ||
| Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs. BTK-CRBN PROTACs act as stoichiometric degraders, resulting in degradation of BTK protein. Degradation of BTK is a result of cereblon E3 ligases family recruitment. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||
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