About 3 results found for searched term "PROTAC BRD4 Degrader-16" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43434 | PROTAC BRD4 Degrader-16 | PROTAC |
| PROTAC BRD4 Degrader-16 is a potent PROTAC BRD4 Degrader, with IC50 values of 34.58 nM (BRD4 (BD1)) and 40.23 nM (BRD4 (BD2)). | ||
| M29586 | KB02-JQ1 | PROTAC |
| KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader (molecular glue), but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1. | ||
| M41643 | PROTAC BRD3/BRD4-L degrader-2 | Epigenetic Reader Domain |
| PROTAC BRD3/BRD4-L degrader-2 is a PROTAC molecule and can selectively degrade cellular BRD3 and BRD4-L with Ki values of 16.91 and 2.8 nM, respectively. | ||
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