About 6 results found for searched term "PPARγ agonist 8" (0.177 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41587 | PPARγ agonist 8 | PPAR |
| PPARγ agonist 8 is an agonist of PPARγ. | ||
| M6602 | Ciglitazone | PPAR |
| ADD-3878; U-63287 | ||
| Ciglitazone is an effective selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibited the proliferation and differentiation of TH17 cells. Ciglitazone is an oral hypoglycemic agent that has been shown to be active in obese hyperglycemic animal models. Ciglitazone induces apoptosis in opossum renal epithelial cells and simultaneously activates nuclear translocation of P38 MAPK and apoptosis-inducing factor (AIF). | ||
| M8539 | G3335 | Others |
| G3335 ( L-tryptophyl-L-glutamic acid) is a cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist with a Kd value of 8. | ||
| M11283 | Inolitazone dihydrochloride | PPAR |
| Efatutazone dihydrochloride; CS-7017 dihydrochloride; RS5444 dihydrochloride | ||
| Inolitazone dihydrochloride (Efatutazone dihydrochloride) is a PPARγ agonist with high affinity, activity dependent on PPARγ, inhibiting growth, IC50 is 0.8 nM. | ||
| M21176 | Leriglitazone | PPAR |
| Hydroxypioglitazone | ||
| Leriglitazone (Hydroxypioglitazone), a metabolite of pioglitazone. Leriglitazone (Hydroxypioglitazone) is a PPARγ agonist that provides high transcriptional potency by stabilizing the PPARγ (AF-2) coactivator binding surface and enhancing coactivator binding capacity. Leriglitazone (Hydroxypioglitazone) binds to PPARγC (LBD) with a Ki value of 1.2 μM and induces PPARγ (LBD) transcriptional efficiency with an EC50 of 680 nM. | ||
| M29393 | Inolitazone | PPAR |
| Efatutazone; CS-7017; RS5444 | ||
| Inolitazone a novel high-affinity PPARγ agonist that is dependent upon PPARγ for its biological activity with IC50 of 0.8 nM for growth inhibition. | ||
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