OSI-420 - Search Results | AbMole BioScience

About 4 results found for searched term "OSI-420" (0.123 seconds)

Cat.No.	Name	Target
M3491	OSI-420	EGFR/HER2
	Desmethyl Erlotinib; CP-473420
	OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
M2622	Desmethyl Erlotinib	Metabolite/Endogenous Metabolite
	Desmethyl Erlotinib (CP-473420, OSI-774) is a free base of OSI-420, the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
M10619	Rhodiosin	AChR/AChE
	Rhodiosin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.420 μM and a Ki of 0.535 μM. Rhodiosin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL.
M28033	ST4206	Adenosine Receptor
	ST4206 is a potent and orally active adenosine A2A receptor antagonist, with Kis of 12 nM and 197 nM for adenosine A2A receptor and adenosine A1 receptor, respectively. ST4206 has the potential for Parkinson׳s disease research.