About 4 results found for searched term "OSI-420" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3491 | OSI-420 | EGFR/HER2 |
| Desmethyl Erlotinib; CP-473420 | ||
| OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). | ||
| M2622 | Desmethyl Erlotinib | Metabolite/Endogenous Metabolite |
| Desmethyl Erlotinib (CP-473420, OSI-774) is a free base of OSI-420, the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). | ||
| M10619 | Rhodiosin | AChR/AChE |
| Rhodiosin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.420 μM and a Ki of 0.535 μM. Rhodiosin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL. | ||
| M28033 | ST4206 | Adenosine Receptor |
| ST4206 is a potent and orally active adenosine A2A receptor antagonist, with Kis of 12 nM and 197 nM for adenosine A2A receptor and adenosine A1 receptor, respectively. ST4206 has the potential for Parkinson׳s disease research. | ||
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