About 5 results found for searched term "OG-L002" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2897 | OG-L002 | Histone demethylase |
| OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. | ||
| M8517 | OG-L002 hydrochloride | Monoamine Oxidase |
| OG-L002 is a recently developed inhibitor with IC50 of 20 nM at LSD1 and much lower activity at MAO-A and MAO-B (1.38 and 0.72 μM, respectively). | ||
| M4852 | LY303511 | mTOR |
| LY303511 is a structural analogue of LY294002, which does not inhibit PI3K, increased homotypic GJIC. | ||
| M8910 | Pamapimod | p38 MAPK |
| R-1503, Ro4402257 | ||
| Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor, inhibited p38alpha and p38beta enzymatic activity, with IC50 values of 0.014 +/- 0.002 and 0.48 +/- 0.04 microM, respectively. | ||
| M9121 | LY303511 hydrochloride | mTOR |
| NV-128; EM 101 hydrochloride | ||
| LY303511 hydrochloride is a structural analogue of LY294002. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. | ||
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