About 2 results found for searched term "Nutlin-3a" (0.649 seconds)
Cat.No. | Name | Target |
---|---|---|
M2894 | Nutlin-3a | Mdm2 |
(-)-Nutlin-3; Rebemadlin | ||
Nutlin-3a, the active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits the p53/MDM2 interaction with IC50 of 90 nM. | ||
M2895 | Nutlin-3b | Mdm2 |
(+)-Nutlin-3 | ||
Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite enantiomer Nutlin-3a. |
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