About 30 results found for searched term "Neurokinin Receptor" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M53050 | Neurokinin Receptor (393-407), rat | Neurokinin Receptor |
| Neurokinin Receptor (393-407), rat (SPR393–407) is a rat neurokinin 1 receptor (NK1R) fragment. | ||
| M1832 | Maropitant | Neurokinin Receptor |
| Maropitant (Cerenia) is a novel, selective neurokinin type-1 (NK1) receptor antagonist. | ||
| M3882 | Netupitant | Neurokinin Receptor |
| CHEBI441603, CID6451149, D05152 | ||
| Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM. | ||
| M9019 | Rolapitant | Neurokinin Receptor |
| SCH 619734 | ||
| Rolapitant (SCH619734) is an orally bioavailable, centrally-acting, selective neurokinin 1 receptor (NK1-receptor) antagonist with a Ki of 0.66 nM. | ||
| M9080 | Substance P | Neurokinin Receptor |
| Neurokinin P; SubstanceP | ||
| Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). | ||
| M9185 | Serlopitant | Neurokinin Receptor |
| VPD-737; MK-0594 | ||
| Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist. | ||
| M10332 | Vapreotide acetate | Neurokinin Receptor |
| BMY-41606; RC160; Octastatin acetate | ||
| Vapreotide acetate (BMY-41606 acetate; RC160 acetate) is a neurokinin-1 (NK1) receptor antagonist with IC50 value of 330 nM. | ||
| M14021 | Fezolinetant | Neurokinin Receptor |
| ESN-364 | ||
| Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. | ||
| M14023 | NKP608 | Neurokinin Receptor |
| NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo. | ||
| M14024 | Substance P TFA | Neurokinin Receptor |
| Neurokinin P TFA | ||
| Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). | ||
| M22349 | Fosaprepitant | Neurokinin Receptor |
| L-758298; MK-0517 | ||
| Fosaprepitant is a precursor compound to Aprepitant and a neurokinin-1 receptor (NK1) antagonist that can be used in studies related to nausea and vomiting. | ||
| M27671 | Vapreotide | Neurokinin Receptor |
| RC160; BMY 41606 | ||
| Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM. | ||
| M28243 | RP 67580 | Neurokinin Receptor |
| RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation. | ||
| M28611 | Benzomalvin A | Neurokinin Receptor |
| Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively. | ||
| M30171 | Hemokinin 1, human | Neurokinin Receptor |
| Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia. | ||
| M30317 | Orvepitant maleate | Neurokinin Receptor |
| GW823296 maleate | ||
| Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. | ||
| M30712 | Rolapitant hydrochloride | Neurokinin Receptor |
| SCH619734 hydrochloride | ||
| Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride does not interact with CYP3A4. Rolapitant hydrochloride shows potent anti-emetic activity in a ferret emesis model. | ||
| M30886 | Rolapitant hydrochloride hydrate | Neurokinin Receptor |
| SCH619734 hydrochloride hydrate | ||
| Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model. | ||
| M31036 | Hemokinin 1, human TFA | Neurokinin Receptor |
| Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human TFA is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human TFA can produces an opioid-independent analgesia. | ||
| M31366 | Elinzanetant | Neurokinin Receptor |
| NT-814 | ||
| Elinzanetant (NT-814) is a first-in-class, orally active dual neurokinin receptor NK1/NK3 antagonist for studies related to hot flushes (HFs). | ||
| M40803 | Pavinetant | Neurokinin Receptor |
| MLE-4901; AZD2624; AZD4901 | ||
| Pavinetant is a neurokinin-3 receptor (NK3R) antagonist that may be used in studies related to hot flashes and polycystic ovary syndrome. | ||
| M41879 | NK3R-IN-1 | Neurokinin Receptor |
| NK3R-IN-1, a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. | ||
| M41880 | FR 113680 | Neurokinin Receptor |
| FR 113680 is a tripeptide substance P antagonist that interacts selectively with the NK1 neurokinin receptor. | ||
| M50874 | Substance P(1-4) | Others |
| Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. | ||
| M53035 | GR 83074 | Neurokinin Receptor |
| GR 83074 is a potent and selective NK-2 (Neurokinin Receptor) antagonist with a pKB of 8.23. | ||
| M53040 | Scyliorhinin II | Neurokinin Receptor |
| Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex. | ||
| M53046 | Neurokinin A(4-10) | Neurokinin Receptor |
| Neurokinin A (4-10) is a tachykinin NK2 receptor agonist. | ||
| M53051 | [D-Trp2, 7, 9] Substance P | Neurokinin Receptor |
| [D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively. | ||
| M53052 | (D-Pro2, D-Trp6, 8, Nle10)-Neurokinin B | Neurokinin Receptor |
| (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. | ||
| M53053 | [MePhe7]-Neurokinin B | Neurokinin Receptor |
| [MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. | ||
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