About 1 result found for searched term "NCB-0846" (0.063 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5279 | NCB-0846 | TNIK |
| NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation. | ||
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