About 9 results found for searched term "Mitogen-activated protein kinase 1" (0.432 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M52815 | Mitogen-activated protein kinase 1 | NF-κB |
| Mitogen-activated protein kinase 1 (MAPK1) can activate the downstream p38/NF-κB pathway. | ||
| M8200 | SB 220025 trihydrochloride | Others |
| SB 220025 is a potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase, with an IC50 value of 60 nM and 50- to 1000-fold selectivity. | ||
| M8910 | Pamapimod | p38 MAPK |
| R-1503, Ro4402257 | ||
| Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor, inhibited p38alpha and p38beta enzymatic activity, with IC50 values of 0.014 +/- 0.002 and 0.48 +/- 0.04 microM, respectively. | ||
| M9160 | BMS-582949 | p38 MAPK |
| PS540446; BMS582949 free base | ||
| BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor with IC50 of 13nM. | ||
| M20176 | WAY-382818 | Others |
| WAY-382818 has mitogen-activated protein kinase phosphatase-1 inhibitory activity. | ||
| M20713 | DMX-5084 | MAPKAPK2/MAP3K/MAP4K |
| DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. | ||
| M20734 | (E/Z)-BCI | Phosphatase |
| BCI, NSC 150117 | ||
| (E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. | ||
| M21660 | MMI-0100 | Others |
| MMI-0100 is a novel cell permeant peptide inhibitor of Mitogen Activated Protein Kinase Activated Protein Kinase II (MK2), MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease. | ||
| M29905 | FgGpmk1-IN-1 | Others |
| FgGpmk1-IN-1 is a novel fusarium graminearum mitogen-activated protein kinase (FgGpmk1) inhibitor with an EC50 value of 3.46 μg/mL. | ||
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