About 4 results found for searched term "MS140" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7659 | BMS-341400 methanesulfonate | Others |
| BMS-341400 is a selective and potent phosphodiesterase 5 (PDE 5) inhibitor. | ||
| M21041 | MS140 | CDK |
| MS140 is a specific and highly potent CDK4/6 kinase inhibitor and also a CDK4/6 degrader (PROTAC). | ||
| M5863 | Pazopanib HCl (GW786034) | VEGFR/PDGFR |
| GW786034; Pazopanib Hydrochloride | ||
| Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. | ||
| M29562 | MS98 | PROTAC |
| MS98 is a potent and selective PROTAC AKT degrader. MS98 depletes cellular total AKT (T-AKT) with the DC50 value of 78 nM. MS98 binds to AKT1, AKT2, and AKT3 with Kds of 4 nM, 140 nM, and 8.1 nM, respectively. | ||
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