MS140 - Search Results | AbMole BioScience

About 5 results found for searched term "MS140" (0.123 seconds)

Cat.No.	Name	Target
M7659	BMS-341400 methanesulfonate	Others
	BMS-341400 is a selective and potent phosphodiesterase 5 (PDE 5) inhibitor.
M21041	MS140	CDK
	MS140 is a specific and highly potent CDK4/6 kinase inhibitor and also a CDK4/6 degrader (PROTAC).
M5863	Pazopanib HCl (GW786034)	VEGFR/PDGFR
	GW786034; Pazopanib Hydrochloride
	Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
M29562	MS98	PROTAC
	MS98 is a potent and selective PROTAC AKT degrader. MS98 depletes cellular total AKT (T-AKT) with the DC50 value of 78 nM. MS98 binds to AKT1, AKT2, and AKT3 with Kds of 4 nM, 140 nM, and 8.1 nM, respectively.
M56065	MS8511	Histone Methyltransferase
	MS8511 is a selective G9a/GLP covalent irreversible inhibitor by targeting a cysteine residue at the substrate binding site, with IC50 values of 100 nM (G9a) and 140 nM (GLP), and Kd values of 44 nM (G9a) and 46 nM (GLP).