About 11 results found for searched term "MNK" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28995 | MNK inhibitor 9 | MNK |
| MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 µM and 0.003 µM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research. | ||
| M49659 | MNK8 | STAT |
| MNK8 is a potent STAT3 (signal transducer and activator of transcription 3) inhibitor. | ||
| M2506 | CGP 57380 | MNK |
| CGP 57380 is potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. | ||
| M6244 | Tomivosertib (eFT-508) | MNK |
| eFT508; Tomivosertib | ||
| Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. | ||
| M9474 | SLV-2436 | MNK |
| SEL-201 | ||
| SLV-2436 (SEL201-88) is a novel ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively. | ||
| M16830 | Orobol | Casein Kinase |
| Orobol is a major soy isoflavone that inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM), as well as PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ). | ||
| M20295 | WAY-305025 | MNK |
| WAY-305025 is a selective Mnk inhibitor. | ||
| M20687 | ETC-206 (AUM 001) | MNK |
| ETC-1907206 | ||
| ETC-206 is an orally available highly selective small-molecule MNK 1/2 inhibitor with IC50s of 64 nM and 86 nM, respectively. | ||
| M30082 | EB1 | MNK |
| EB1 is the inhibitor of kinases MNK with IC50s of 0.69 μM (MNK1) and 9.4 μM (MNK2). EB1 selectively inhibits the growth of cancer cells, but not normal cells. EB1 also increases cell apoptosis and suppresses eIF4E phosphorylation. | ||
| M50776 | Antiflammin 3 | Others |
| Antiflammin 3 is an anti-inflammatory peptide 3 (MQMNKVLDS). | ||
| M56440 | DS12881479 | MNK |
| DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. | ||
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