About 6 results found for searched term "MKI-1" (0.208 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14557 | CaMKII-IN-1 | CaMK |
| CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. | ||
| M57051 | MKI-1 | Others |
| MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer. | ||
| M6145 | BMS-5 | LIM Kinase |
| LIMKI 3 | ||
| BMS-5 (LIMKi 3) is a potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). | ||
| M24787 | Olamkicept | Fusion Proteins |
| FE 999301; gp130-Fc; TJ301 | ||
| Olamkicept (FE 999301) is a selective inhibitor of the soluble interleukin 6 (sIL-6R)/IL-6 complex. Olamkicept is a soluble gp130-Fc-fusion-protein and anti-inflammatory agent. | ||
| M49437 | Afimkibart | TNF Receptor |
| PF-06480605; RVT-3101 | ||
| Afimkibart (PF-06480605) is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC). | ||
| M58684 | Delgrandine | Alkaloids |
| Delgrandine is a Alkaloids product that can be isolated from the herbs of Delphinium davidii. Delgrandine demonstrates high binding affinities for GRIN2B (also known as NMDAR2B) and ERK. Delgrandine displayed a high affinity for CAMK2A (also known as CaMKIIα). Delgrandine exhibited high binding affinity with NMDAR2B (−11 kcal/mol), CaMKIIα (−14.3 kcal/mol), and ERK (−10.8 kcal/mol). | ||
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