About 7 results found for searched term "MAGL-IN-5" (0.178 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29986 | MAGL-IN-5 | MAGL |
| CAY10499 | ||
| MAGL-IN-5 (CAY10499) is a non-selective lipase inhibitor with IC50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL),hormone sensitive lipase(HSL), and fatty acid amide hydrolase(FAAH) respectively. | ||
| M4890 | JZL 195 | MAGL |
| GTPL8606, KB-78011 | ||
| JZL195 is an effective FAAH and MAGL inhibitor with IC50 of 2 nM and 4 nM, respectively. | ||
| M6853 | JW 642 | MAGL |
| Jw642 is a highly effective selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6 nM, 14 nM and 3.7 nM in mouse, rat and human meninges, respectively. | ||
| M13369 | ABX-1431 | MAGL |
| ABX-1431 is a highly potent, selective and orally available CNS-osmotic monacylglycerol lipase (MAGL) inhibitor with IC50 values of 14 nM and 27 nM against human and mouse MGLL, respectively. | ||
| M13370 | KML-29 | MAGL |
| KML29 is an effective selective MAGL inhibitor with IC50 values of 15 nM, 43 nM and 5.9 nM in mice, rats and humans, respectively. KML29 has minimal cross-reaction with other central and peripheral serine hydrolases including FAAH. | ||
| M29167 | PF-06795071 | MAGL |
| PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM. | ||
| M29617 | MAGL-IN-6 | MAGL |
| MAGL-IN-6 is a potent MAGL inhibitor with an IC50 of 4.71 nM. MAGL-IN-6 can be used for neurological disorders research (WO2020065613A1; example 234). | ||
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