About 13 results found for searched term "Linoleic acid" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11327 | ABTL-0812 | Autophagy |
| α-Hydroxylinoleic acid | ||
| Abtl-0812 (α -hydroxylinoleic acid) induces ER stress-mediated autophagy and has anticancer activity. ABTL0812 is a first-in-class small molecule with anti-cancer activity. | ||
| M14382 | Linoleic acid | Metabolite/Endogenous Metabolite |
| Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. | ||
| M30475 | Linoleoyl ethanolamide | Cannabinoid |
| Linoleic acid monoethanolamide | ||
| Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time. | ||
| M4118 | Hederacolchiside-E | Others |
| Hederacolicide E had antioxidant activity and inhibited lipid peroxidation of linoleic acid emulsions. It may exert its anti-inflammatory effects by blocking bradykinin or other inflammatory mediators. | ||
| M8371 | 9(S)-HODE | Others |
| 9(S)-HODE is produced by the lipoxygenation of linoleic acid. | ||
| M9452 | Sulfaphenazole | Anti-infection |
| Sulfaphenazolum | ||
| Sulfaphenazole is an inhibitor of CYP2C9, which blocks atherogenic and pro-inflammatory effects of linoleic acid mediated by CYP2C9. | ||
| M9568 | SC-26196 | Others |
| SC26196 | ||
| SC-26196 is a potent, orally active D6D inhibitor (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). | ||
| M10761 | DC260126 | Apoptosis |
| DC260126 is a potent GPR40 (FFAR1) antagonist. DC260126 dose-dependent inhibits GPR40-mediated Ca of linoleic acid, oleic acid, palm oleic acid, and lauric acid irritation2+ ELEVATED (IC50 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 is protective of palmitate-induced endoplasmic reticulum stress and apoptosis ( apoptosis ) . | ||
| M20891 | Grape Seed Extract | Others |
| Grape Seed Extract are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs. | ||
| M22486 | AH-7614 | GPR/FFAR |
| AH7614 | ||
| AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist. | ||
| M42368 | 13-Hydroxyoctadecadienoic acid | Metabolite/Endogenous Metabolite |
| 13-hydroxyoctadecadienoic acid (13-HODE) is an endogenous lipoxygenase metabolite of Linoleic acid. | ||
| M45337 | ALOX15-IN-2 | Lipoxygenase |
| ALOX15-IN-2 is a potent inhibitor of rabbit and human ALOX15 linoleate oxygenase activity, with IC50s of 1.55 and 2.79 μM for linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, respectively. | ||
| M49924 | Bovinic acid | Metabolite/Endogenous Metabolite |
| Bovinic acid is a conjugated linoleic acid with anti-cancer and anti-atherosclerotic activity. | ||
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