About 1 result found for searched term "JH-XI-10-02 " (0.119 seconds)
Cat.No. | Name | Target |
---|---|---|
M29357 | JH-XI-10-02 | PROTAC |
JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK. JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. |
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