About 1 result found for searched term "JH-XI-10-02 " (0.075 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29357 | JH-XI-10-02 | PROTAC |
| JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK. JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. | ||
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