About 6 results found for searched term "JAK-2/3-IN-3" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49504 | JAK-2/3-IN-3 | Apoptosis |
| JAK-2-/3-IN-3 is a potent JAK2/3 inhibitor with IC50s of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. | ||
| M28195 | JAK-IN-1 | JAK |
| JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1. | ||
| M49559 | AT9283 lactic acid | JAK |
| AT9283 lactic acid is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM). | ||
| M49579 | JAK-2/3-IN-1 | JAK |
| JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of <250 nM for both isoforms. | ||
| M49580 | JAK-2/3-IN-2 | JAK |
| JAK-2/3-IN-2 is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively. | ||
| M49776 | SJ10542 | PROTAC |
| SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. | ||
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