About 3 results found for searched term "J-113863" (0.205 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6840 | J-113863 | CCR |
| J113863 | ||
| J-113863 is a potent CCR1 chemokine receptor antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). | ||
| M56158 | cis-J-113863 | CCR |
| cis-J-113863 is a competitive chemokine receptor 1 (CCR1) antagonist, with IC50 values of 0.9 and 5.8 nM for human and mouse CCR1 receptors, respectively. | ||
| M56156 | trans-J-113863 | CCR |
| trans-J-113863 is a potent chemokine CCR1 and CCR3 receptor antagonist, and inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC50 of 9.57 and 93.8 nM,respectively. | ||
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