About 2 results found for searched term "Ivarmacitinib" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28457 | Ivarmacitinib | JAK |
| SHR0302 | ||
| Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects. | ||
| M49567 | Ivarmacitinib sulfate | JAK |
| Ivarmacitinib (SHR0302) sulfate is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. | ||
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