About 3 results found for searched term "Indirubin-3'-monoxime" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10108 | Indirubin-3'-monoxime | GSK-3 |
| I3MO | ||
| Indirubin-3'-monoxime is a potent GSK-3β inhibitor with IC50 of 22 nM, and inhibits Cdk5/p35, Cdk1/cyclin-B and Cdk2/cyclin-E with IC50s of 100, 180, 250 nM. | ||
| M49515 | Indirubin-3'-monoxime-5-sulphonic acid | CDK |
| Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively. | ||
| M49750 | 5-Iodo-indirubin-3'-monoxime | GSK-3 |
| 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively. | ||
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