About 16 results found for searched term "IRAK inhibitor 2" (0.509 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54674 | IRAK inhibitor 2 | IRAK |
| IRAK inhibitor 2 is an interleukin-1 receptor-related kinase 4 (IRAK4) inhibitor. | ||
| M54679 | IRAK-4 protein kinase inhibitor 2 | IRAK |
| IRAK-4 protein kinase inhibitor 2 is a potent interleukin 1 (IL-1) receptor-associated kinase 4 (IRAK-4) inhibitor with an IC50 value of 4 μM.IRAK-4 protein kinase inhibitor 2 can be used in the study of inflammatory and immune-related diseases. | ||
| M9340 | IRAK-1-4 Inhibitor I | IRAK |
| IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.3 μM and 0.2 μM, respectively. | ||
| M14092 | IRAK4-IN-4 | IRAK |
| IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 of 2.8 nM. | ||
| M20764 | HS-243 | IRAK |
| HS-243 is a highly potent interleukin-1 receptor-associated kinase (IRAK) inhibitor with IC50 of 24 nM, 20 nM and 0.5 μM for IRAK-1, IRAK-4 and TAK1, respectively. | ||
| M21388 | IRAK4-IN-20 | IRAK |
| IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. IRAK4-IN-20 may be used in studies of acute respiratory distress syndrome (ARDS). | ||
| M21784 | AZ1495 | IRAK |
| AZ1495 is a weak base and orally active, potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with a Kd value of 0.0007 μM.AZ1495 has good physicochemical and kinase selectivity for IRAK4 and IRAK1, with IC50 values of 0.005 μM and 0.023 μM, respectively.AZ1495 is used in studies of diffuse large B-cell lymphoma (DLBCL). | ||
| M27696 | IRAK inhibitor 1 | IRAK |
| IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively. | ||
| M29213 | GLPG2534 | IRAK |
| GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4. GLPG2534 can be used for the research of inflammatory skin diseases. | ||
| M29657 | IRAK4-IN-6 | IRAK |
| IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma. | ||
| M41998 | IRAK4-IN-25 | IRAK |
| IRAK4-IN-25 is an orally acitve and potent IRAK4 inhibitor (IC50=7.3 nM), with low clearance (Cl=12 mL/min/kg). | ||
| M42004 | IRAK4-IN-26 | IRAK |
| IRAK4-IN-26 is a IRAK4 inhibitor (IC50: 6.2 nM). | ||
| M54681 | IRAK4-IN-21 | IRAK |
| IRAK4-IN-21 is an orally potent, selective, and potent IRAK4 inhibitor with IC50 values of 5 and 56 nM for IRAK4 and TAK1, respectively.IRAK4-IN-21 potently inhibits the production of IL-23 (IC50=0.17 µM) and may be useful in studies related to autoimmune diseases such as plaque psoriasis and psoriasis vulgaris. arthritis). | ||
| M54685 | IRAK4-IN-22 | IRAK |
| IRAK4-IN-22 is an orally potent and selective potent IRAK4 inhibitor with IC50 values of 3 and 17 nM for IRAK4 and TAK1, respectively.In addition, IRAK4-IN-21 potently inhibits the production of IL-23 (IC50=0.10 µM), which may be useful in studies related to autoimmune diseases such as plaque psoriasis and psoriasis vulgaris. arthritis). | ||
| M54684 | HS271 | IRAK |
| HS271 is an orally potent and selective IRAK4 inhibitor with an IC50 value of 7.2 μM. In addition, HS271 has superior in vitro enzymatic and cellular activities. | ||
| M56368 | HS-243 | IRAK |
| HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor, with IC50 values of 20 and 24 nM. | ||
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