About 4 results found for searched term "IDH1 Inhibitor 8" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54529 | IDH1 Inhibitor 8 | Isocitrate Dehydrogenase (IDH) |
| IDH1 Inhibitor 8 is an isocitrate dehydrogenase 1 (IDH1) inhibitor that can be used in cancer-related studies. | ||
| M10335 | IDH-305 | Isocitrate Dehydrogenase (IDH) |
| IDH305 | ||
| IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1(R132) mutation with IC50 values of 27 nM, 28 nM and 6.14 μM for IDH1R132H, IDH1R132C and IDH1WT, respectively. | ||
| M14454 | Mutant IDH1-IN-1 | Isocitrate Dehydrogenase (IDH) |
| Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively. | ||
| M54537 | Mutant IDH1-IN-4 | Isocitrate Dehydrogenase (IDH) |
| Mutant IDH1-IN-4 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH 1) with an IC50 value of ≤ 0.5 μM for mutant IDH 1 in R132H, HT1080 and U87R132H cells. | ||
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