About 1 result found for searched term "IACS-13909" (0.134 seconds)
Cat.No. | Name | Target |
---|---|---|
M10738 | IACS-13909 | Phosphatase |
IACS-13909 is a potent selective, orally active SHP2 allosteric inhibitor IC50 for 15.7 nM,Kd 32 nM. IACS-13909 is more selective for SHP2 than other phosphatase, including SHP1. IACS-13909 inhibits the signaling of the receptor tyrosine kinase (RTK)/MAPK pathway and has an anticancer effect. |
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