About 3 results found for searched term "HSP90-IN-22" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41508 | HSP90-IN-22 | HSP |
| HSP90-IN-22 is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively. | ||
| M2003 | PF-04929113 | HSP |
| SNX-5422 | ||
| PF-04929113 (SNX-5422) is a potent and selective Hsp90 inhibitor with Kd of 41 nM. SNX-5422 (PF-04929113) also induces Her-2 degradation, with an IC50 of 37 nM. | ||
| M28600 | HS-27 | HSP |
| HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer. | ||
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