About 5 results found for searched term "HSP90-IN-21" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41214 | HSP90-IN-21 | Parasite |
| HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. | ||
| M1762 | Luminespib (AUY922) | HSP |
| NVP-AUY922; Luminespib | ||
| Luminespib (AUY922) is a small molecule Heat Shock Protein 90 (HSP90) inhibitor with IC50 values of 13 and 21 nM for HSP90α and HSP90β respectively. | ||
| M2776 | IPI-493 | HSP |
| IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM. | ||
| M13684 | VER-50589 | HSP |
| VER-50589 is a Hsp90 inhibitor, with an IC50 of 21 nM and a Kd of 4.5 nM. | ||
| M20676 | Pimitespib | HSP |
| TAS-116 | ||
| TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L). | ||
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