About 2 results found for searched term "HPK1-IN-38" (0.09 seconds)
Cat.No. | Name | Target |
---|---|---|
M42135 | HPK1-IN-38 | MAPKAPK2/MAP3K/MAP4K |
HPK1-IN-38 is a MAP4K1/HPK1 inhibitor, can be used for HPK1 related disorders research. | ||
M10832 | HPK1-IN-7 | MAPKAPK2/MAP3K/MAP4K |
HPK1-IN-7 is a potent inhibitor of the orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) (IC50=2.6 nM), with excellent family and kinase group selectivity. The HPK1-IN-7 is selective for IRAK4 (59 nM) and GLK (140 nM). HPK1-IN-7 combined with anti-PD1 has shown powerful efficacy in MC38 cogenic tumor models. |
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