About 8 results found for searched term "HDAC-IN-57" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41481 | HDAC-IN-57 | HDAC |
| HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. | ||
| M9217 | Givinostat | HDAC |
| ITF2357 | ||
| Givinostat (ITF-2357) is an HDAC inhibitor with IC50s of 198 and 157 nM for HDAC1 and HDAC3, respectively. | ||
| M2236 | CI-994 | HDAC |
| Tacedinaline, PD 123654 | ||
| CI-994 (N-acetyl dinaline, PD 123654) is a novel orally active HDAC inhibitor with IC50 of 0.57 μM for HDAC1. | ||
| M3095 | Tubastatin A | HDAC |
| Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). | ||
| M3643 | TMP269 | HDAC |
| TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.In addition, TMP269 significantly promotes reprogramming. | ||
| M13670 | Domatinostat tosylate | HDAC |
| 4SC-202 | ||
| Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). | ||
| M20718 | Tubastatin A TFA | HDAC |
| Tubastatin A trifluoroacetate salt | ||
| Tubastatin A TFA (Tubastatin A trifluoroacetate salt) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). Tubastatin A promotes autophagy and increases apoptosis. | ||
| M29087 | Givinostat hydrochloride | HDAC |
| ITF-2357 hydrochloride | ||
| Givinostat (ITF-2357) hydrochloride is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. | ||
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