HDAC-IN-30 - Search Results | AbMole BioScience

About 7 results found for searched term "HDAC-IN-30" (0.124 seconds)

Cat.No.	Name	Target
M53351	HDAC-IN-30	HDAC
	HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 (IC50=13.4 nM),HDAC2 (IC50=28.0 nM), HDAC3 (IC50=9.18 nM), HDAC6 (IC50=42.7 nM), HDAC8 (IC50=131 nM).
M3405	AR-42	HDAC
	HDAC-42
	AR-42 is an HDAC inhibitor with IC50 of 30 nM.
M6176	TMP195	HDAC
	TFMO 2
	TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays.
M8594	BRD3308	HDAC
	BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23 times more selective to HDAC3 than HDAC1 (IC50:1.26 μM) or HDAC2 (IC50:1.34 μM). BRD3308 inhibits pancreatic β cell apoptosis induced by inflammatory cytokines or glucolipid toxic stress and increases functional insulin release. BRD3308 also activates HIV-1 transcription and disrupts HIV-1 latency.
M20389	Quisinostat (JNJ-26481585) 2HCl	HDAC
	Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11 greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
M41482	HDAC6-IN-17	HDAC
	HDAC6-IN-17 is a potent HDAC6 inhibitor with IC50 values of 150 nM, 1400 nM, and 2300 nM for HDAC6, HDAC8, and HDAC4, respectively.
M43512	HDAC-IN-63	FLT3
	HDAC-IN-63 is a dual FLT3/HDAC inhibitor (IC50: 0.844 and 30.0 nM for FLT3 and HDAC1 respectively).