About 13 results found for searched term "Glycoside-O-4" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4137 | Glycoside-O-4 | Others |
| Glycoside-O-4 | ||
| M4414 | Gentiopicrin | Cytochrome P450 (e.g. CYP17) |
| Gentiopicroside is a natural iridoid glycoside that can inhibit the activity of P450 with IC50 and Ki values of 61 µM and 22.8 µM for CYP2A6, respectively. Gentiopicroside has anti-inflammatory and antioxidant activities. | ||
| M4443 | Spinosin | Amyloid |
| Spinosyn is a neuroprotective C-glycoside flavonoid isolated from the seeds of Zizyphus jujube. Spinosyn inhibits the production and polymerization of Aβ1-42 by activating the Nrf2/HO-1 pathway. | ||
| M4598 | Rhoifolin | Insulin Receptor |
| RhoifolinRhoifolin is a flavonoid glycoside isolated from the leaves of Guanxi pomelo (Citrus Grandis). Rhoifolin is beneficial to diabetic complications by enhancing adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and translocation of GLUT4. Rhoifolin ameliorates titanium-stimulated osteolysis and attenuates osteoclast formation through ranKL-induced NF-κB and MAPK pathways. | ||
| M4731 | Poliumoside | Aldose Reductase |
| Poliumoside, a coffee-acylated phenylpropane glycoside isolated from the stems and leaves of Brandisia hancei. Poliumoside inhibited the formation of advanced glycation end products (AGE) and rat lens aldose reductase (RLAR) with IC50 values of 19.69 and 8.47 μM, respectively. Poliumoside also has anti-inflammatory and antioxidant activities. | ||
| M4759 | Tiliroside | Others |
| Tiliroside is a glycoside flavonoid with antidiabetic properties. Tiliroside is a noncompetitive inhibitor of α-amylase with a Ki value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract. | ||
| M5174 | Icariin | PDE |
| 8-prenyl kaempferol 3,7-O-diglucoside | ||
| Icariin is a flavonol glycoside. Icariin inhibited PDE5 and PDE4 activity with IC50 of 432 nM and 73.50 μM, respectively. Icariin is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism. | ||
| M11528 | Naringin | Cytochrome P450 (e.g. CYP17) |
| Naringoside | ||
| Naringin, a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes. | ||
| M14998 | Isorhamnetin 3-O-galactoside | Others |
| Cacticin | ||
| Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. | ||
| M19328 | Hibifolin | Adenosine Deaminase |
| Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity. | ||
| M29038 | Isosaponarin | TGF-β Receptor |
| Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin increases collagen synthesis, caused by up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production. | ||
| M30165 | Indican | Fluorescent Dye |
| Indoxyl-β-D-glucoside | ||
| Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4. | ||
| M40128 | Cymarin | Others |
| Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM). | ||
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