About 12 results found for searched term "Gly-Sar" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M51788 | H-Gly-Sar-Sar-OH | Amino Acid Derivatives |
H-Gly-Sar-Sar-OH is an orally active tripeptide. | ||
M54380 | Gly-Sar | Amino Acid Derivatives |
Gly-Sar is a Glycine derivative. | ||
M1657 | Atazanavir Sulfate | HIV Protease |
BMS-232632, Reyataz, CGP-73547 | ||
Atazanavir sulfate (BMS-232632, Reyataz) is an azapeptide inhibitor of HIV-1 protease. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. | ||
M4528 | Rosarin | IL Receptor/Related |
Rosarin is a cinnamyl glycoside isolated from rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin inhibited the expression of iNOS, IL-1β and TNF-α in the kidney and prefrontal cortex of mice. | ||
M5427 | Atazanavir | HIV Protease |
BMS-232632; Latazanavir; Zrivada; Reyataz | ||
Atazanavir (BMS-232632) is an azapeptide and HIV-protease inhibitor. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. | ||
M10884 | YH-53 | Anti-infection |
YH-53 IS AN EFFECTIVE ONE 3CLpro Inhibitor, 3CL against SARS-CoV-1pro and SARS-CoV-2 3CLpro target Ki The values are 6.3 nM and 34.7 nM, respectively. YH-53 strongly blocks SARS-CoV-2 replication. YH-53 is a peptide-mimetic compound with unique benzothiazolidinone. | ||
M21967 | Cefepime | Antibiotic |
BMY-28142 | ||
Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. | ||
M25151 | Beludavimab | Anti-infection |
BMS 4182137; VIR 7832 | ||
Beludavimab (BMS 4182137; VIR 7832) is a monoclonal antibody targeting the spike glycoprotein of SARS-CoV-2. Beludavimab binds to recombinant spike protein receptor-binding domain (S-RBD) with an EC50 value of 14.9 ng/mL and a Kd of 0.21 nM. | ||
M25189 | Lomtegovimab | Anti-infection |
BI 767551; DZIF-10c | ||
Lomtegovimab (BI 767551) is a humanized anti-SARS-COV-2 spike glycoprotein monoclonal antibody. Lomtegovimab binds and neutralizes SARS-CoV-2. Lomtegovimab shows antiviral efficacy. Lomtegovimab has the potential for the research of COVID-19. | ||
M25197 | Ogalvibart | Anti-infection |
C-135-LS; BMS-986414 | ||
Ogalvibart (C-135-LS) is a humanized anti-SARS-CoV-2 monoclonal antibody (IgG1 type). Ogalvibart binds to the spike (S) glycoprotein receptor-binding domain (RBD) of SARS-CoV-2. Ogalvibart in combination with C144LS (1:1 ratio) shows good preventive activity and can effectively block the development of COVID19 in a rhesus monkey disease model. | ||
M27967 | SAR629 | MAGL |
SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation. | ||
M53431 | Z-Arg-Leu-Arg-Gly-Gly-AMC | Anti-infection |
Z-Arg-Leu-Arg-Gly-Gly-AMC is a peptide substrate of SARS-CoV PLpro. |
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