About 24 results found for searched term "Glucokinase" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M50297 | Glucokinase | Enzymes & Coenzymes |
| Glucokinase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M3562 | LY2608204 | Glucokinase (GK) |
| Globalagliatin | ||
| LY2608204 activates glucokinase (GK) with EC50 of 42 nM. | ||
| M6751 | GKA 50 | Glucokinase (GK) |
| GKA 50 is a glucokinase activator. | ||
| M7116 | PF 04991532 | Glucokinase (GK) |
| PF 04991532 is a potent hepatoselective glucokinase activator. | ||
| M7567 | AM2394 | Glucokinase (GK) |
| AM-2394 is a structurally distinct glucokinase activator (GKA). AM-2394 activates glucokinase (GK) with an EC50 of 60 nM. | ||
| M8096 | PF-04937319 | Others |
| PF-04937319 is a glucokinase activator with an EC50 value of 174 nM. | ||
| M10047 | Dorzagliatin | Glucokinase (GK) |
| HMS5552; RO5305552; Sinogliatin | ||
| Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes. | ||
| M10305 | AZD1656 | Glucokinase (GK) |
| AZD-1656 | ||
| AZD1656 is a potent, selective and orally active glucokinase (GK) activator, with an EC50 of 60 nM. | ||
| M14436 | AMG-3969 | Others |
| AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM. | ||
| M14437 | RO-28-1675 | Glucokinase (GK) |
| RO-28-1675 is a potent allosteric glucokinase (GK) activator with an EC50 of 54 nM. RO-28-1675 can be used for the research of type 2 diabetes. | ||
| M20086 | WAY-320080 | Glucokinase (GK) |
| WAY-320080 is a glucokinase activator | ||
| M20087 | WAY-320081 | Glucokinase (GK) |
| WAY-320081 is a glucokinase activator | ||
| M20368 | WAY-297848 | Glucokinase (GK) |
| WAY-297848 is a glucokinase activator. | ||
| M20373 | WAY-615145 | Glucokinase (GK) |
| WAY-615145 is a glucokinase activator. | ||
| M21065 | BMS-820132 | Others |
| BMS-820132 is an oral glucokinase (GK) partial activator for the study of diabetes mellitus. the AC50 is 29 nM. | ||
| M21626 | Cadisegliatin (TTP-399) | Glucokinase (GK) |
| TTP-399 | ||
| Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes. | ||
| M27831 | MK-0941 | Glucokinase (GK) |
| MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes. | ||
| M28249 | AMG-1694 | Glucokinase (GK) |
| AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity and promotes GK translocation. AMG-1694 normalizes blood glucose levels in several rodent models of diabetes and lowes blood glucose restricted to diabetic and not normoglycaemic animals. | ||
| M30576 | MK-0941 free base | Glucokinase (GK) |
| MK-0941 free base is an orally active glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 free base exhibits strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes. | ||
| M30958 | 3-O-Methyl-N-acetyl-D-glucosamine | Others |
| 3-O-Methyl-GlcNAc | ||
| 3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine. | ||
| M31408 | PB-201 | Glucokinase (GK) |
| PB-201 is a glucokinase activator (GKA) that can be used in studies related to type 2 diabetes. | ||
| M31409 | TMG-123 | Glucokinase (GK) |
| TMG-123 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes. | ||
| M31411 | GKM-001 | Glucokinase (GK) |
| GKM-001 is a glucokinase (GK) activator that can be used in studies related to type 2 diabetes. | ||
| M42408 | AZD1092 | Glucokinase (GK) |
| AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM. | ||
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