About 20 results found for searched term "Ginsenoside-F2" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4084 | Ginsenoside-F2 | Apoptosis |
| Ginsenoside F2, a metabolite of Ginsenoside Rb1, induces apoptosis and protective autophagy in breast cancer stem cells. | ||
| M39962 | Notoginsenoside FP2 | Others |
| Notoginsenoside FP2, a dammarane-Type Bisdesmoside isolated from the Fruit Pedicels of Panax notoginseng, has potential to treat cardiovascular disease. | ||
| M4065 | Ginsenoside-Rb2 | Anti-infection |
| Ginsenoside C | ||
| Ginsenoside Rb2 is one of the main bioactive components of ginseng extract. Ginsenoside Rb2 can up-regulate GPR120 gene expression. Ginsenoside Rb2 has antiviral effects. | ||
| M4066 | Ginsenoside-Rb3 | NF-κB |
| Gypenoside IV | ||
| Ginsenoside Rb3 is derived from Panax Notoginseng. Ginsenoside Rb3 inhibited NF-κB transcriptional activity induced by TNFα in 293T cell lines with IC50 of 8.2 μM. Ginsenoside Rb3 also inhibited the induction of COX-2 and iNOS mRNA. | ||
| M4068 | Ginsenoside-Rg3 | Sodium Channel |
| 20(S)-Ginsenoside-Rg3; Rg3; S-Ginsenoside Rg3 | ||
| 20(S)-Ginsenoside Rg3 is the main ingredient of red ginseng. 20(S) -ginsenoside Rg3 inhibited Na+ and hKv1.4 channels with IC50 of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S) -ginsenoside Rg3 also inhibited Aβ, NF-κB activity and COX-2 expression. | ||
| M4072 | Ginsenoside-Rh3 | Keap1-Nrf2 |
| Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 induces Nrf2 activation in human retinal cells. | ||
| M4075 | Ginsenoside-Rd | NF-κB |
| Gypenoside VIII | ||
| Ginsenoside Rd inhibited NF-κB transcriptional activity induced by TNFα with IC50 of 12.05±0.82 μM. Ginsenoside Rd inhibited the expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibited CYP2D6, CYP1A2, CYP3A4 and CYP2C9 with IC50 of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM and 85.1±9.1 μM, respectively. | ||
| M4076 | Ginsenoside-Rf | Calcium Channel |
| Panaxoside Rf | ||
| Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channels. | ||
| M4079 | (R)Ginsenoside-Rh2 | MMP |
| 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68. | ||
| M4082 | Protopanaxtriol | Others |
| 20(R)-APPT; 20(R)-Protopanaxatriol | ||
| 20(R)-Protopanaxatriol is a natural ginsenoside ligand of Re, Rf, Rg1, Rg2 and Rh. | ||
| M4083 | Ginsenoside-F1 | Cytochrome P450 (e.g. CYP17) |
| 20(S)-Ginsenoside F1 | ||
| Ginsenoside F1 is an enzymatically modified derivative of Ginsenoside Rg1. Ginsenoside F1 competently inhibits CYP3A4 and has a weak inhibitory effect on CYP2D6. | ||
| M4085 | Ginsenoside-F3 | IL Receptor/Related |
| Ginsenoside F3, a saponin extracted from Panax ginseng leaves, exerts immune-enhancing activity by regulating the production and expression of il-2 (IFN-γ) and IL-4 and IL-10. | ||
| M4088 | Ginsenoside Compound-K | COX |
| Ginsenoside K; Ginsenoside C-K | ||
| Ginsenoside Compound-K is a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. | ||
| M4089 | Ginsenoside-Ro | Calcium Channel |
| Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V; Ginsenoside-Ro | ||
| Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. | ||
| M4090 | Ginsenoside-Rg5 | IGF-1R |
| Ginsenoside Rg5 is the main ingredient of red ginseng. Ginsenoside Rg5 blocks the binding of IGF-1 to its receptor with an IC50 of about 90 nM. Ginsenoside Rg5 also inhibited COX-2 mRNA expression by inhibiting DNA binding activity of NF-κB P65. | ||
| M4091 | Ginsenoside-Rg6 | NF-κB |
| Ginsenoside Rg6 inhibited NF-κB transcriptional activity induced by TNF-α in HepG2 cells with IC50 of 29.34 μM. Ginsenoside Rg6 also induced apoptosis. | ||
| M4092 | Ginsenoside-Rk1 | NF-κB |
| Ginsenoside Rk1 is a high-temperature processed extract of ginseng. Ginsenoside Rk1 has anti-inflammatory effects and inhibits Jak2/Stat3 signaling pathway and NF-κB activation. | ||
| M17765 | Ginsenoside Rk3 | NF-κB |
| Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. | ||
| M39971 | Vinaginsenoside R8 | Others |
| Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC50=25.18 μM). | ||
| M39972 | Notoginsenoside T5 | Others |
| Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng. | ||
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