About 3 results found for searched term "GPX4-IN-6" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42430 | GPX4-IN-6 | Glutathione Peroxidase |
| GPX4-IN-6 is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM. | ||
| M10586 | JKE-1674 | Ferroptosis |
| JKE1674 | ||
| JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1. | ||
| M29297 | PKUMDL-LC-101-D04 | Glutathione Peroxidase |
| GPX4-Activator-1d4; PKU | ||
| PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts. | ||
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