About 31 results found for searched term "GABA Receptor" (0.11 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28615 | GABAA receptor agent 1 | GABA Receptor |
| GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity. | ||
| M2005 | (R)-Baclofen | GABA Receptor |
| STX 209; Arbaclofen | ||
| (R)-baclofen, a gamma-aminobutyric acid derivative and agonist at GABA-B receptors, inhibits nerve conduction in the central nervous system and can be used in studies related to spasticity. | ||
| M2347 | (+)-Bicuculline | GABA Receptor |
| d-Bicuculline | ||
| (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. | ||
| M4013 | Glabridin | GABA Receptor |
| Glabridin, one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory. | ||
| M4019 | Songorine | GABA Receptor |
| Songorine is a diterpenoid alkaloid isolated from the genus Aconite. Songorine is a GABAA receptor antagonist in rat brain and has anticancer, anti-arrhythmia and anti-inflammatory activities. Songorine has potential to be used in epithelial ovarian cancer (EOC) studies. | ||
| M4073 | Ginsenoside-Rc | GABA Receptor |
| Panaxoside Rc | ||
| Ginsenoside Rc is one of the major ginsenosides. Ginsenoside Rc enhances GABA receptor A (GABAA) -mediated ion channel (IGABA) currents. Ginsenoside Rc also inhibited TNF-α and IL-1β expression. | ||
| M4950 | Topiramate | GluR |
| McN 4853; RWJ 17021 | ||
| Topiramate is an anticonvulsant that antagonizes GluR5 receptors and acts as a positive allosteric modulator of GABA receptor-mediated currents. | ||
| M5378 | Acamprosate calcium | GABA Receptor |
| Calcium N-acetylhomotaurinate | ||
| Acamprosate calcium (Campral EC) is a GABA receptor agonist and glutamate system modulator. | ||
| M5390 | Afloqualone | GABA Receptor |
| Afloqualone is a agonist of GABA receptor . | ||
| M5442 | Baclofen | GABA Receptor |
| Baclofen is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research. | ||
| M5575 | Dihydroergotoxine mesylate | GABA Receptor |
| Ergoloid mesylates | ||
| Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. | ||
| M5653 | Flumazenil | GABA Receptor |
| Ro 15-1788 | ||
| Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. | ||
| M5870 | Pentylenetetrazol | GABA Receptor |
| Pentylenetetrazole, Metrazole, pentetrazol | ||
| Pentylenetetrazol displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist. | ||
| M6195 | Propofol | GABA Receptor |
| 2,6-Diisopropylphenol | ||
| Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties. | ||
| M6385 | AA 29504 | Others |
| AA 29504 is a positive allosteric modulator of GABA A receptors. | ||
| M6583 | CGP 36216 hydrochloride | Others |
| CGP 36216 hydrochloride is a gABA B antagonist; displays activity at presynaptic receptors. | ||
| M6720 | Etifoxine hydrochloride | GABA Receptor |
| HOE 36-801 | ||
| Etifoxine hydrochloride is a ligand of the translocator protein (TSPO); also GABAA receptor potentiator. | ||
| M6735 | Flupirtine maleate | Potassium Channel |
| Flupirtine maleate is a selective potassium channel opener, NMDA receptor antagonist and GABAA receptor modulator. | ||
| M6744 | Ganaxolone | GABA Receptor |
| CCD 1042 | ||
| Ganaxolone (CCD 1042) is A neuroactive steroid allopregnenolone analogue synthesized orally and is A selective, high-affinity positive sex modulator of γ -aminobutyrate-A (GABAA) receptor with anticonvulsant properties. Gannadone works through different binding sites with benzodiazepine binding sites and can be used in epilepsy studies related to cyclin-dependent kinase-like 5 (CDKL5) deficiency (CDD). | ||
| M6828 | Indiplon | Others |
| Indiplon is a subtype-selective GABA A receptor positive allosteric modulator. | ||
| M6915 | Loreclezole hydrochloride | Others |
| Loreclezole hydrochloride is a subtype-selective GABA A receptor modulator. | ||
| M6961 | MK 0343 | Others |
| MK 0343 is a subtype-selective GABA A receptor partial agonist. | ||
| M6995 | MRK 016 | GABA Receptor |
| MRK 016 is a gABAA receptor inverse agonist selective for the α5-subtype (EC50 = 3 nM). | ||
| M7087 | Org 20599 | Others |
| Org 20599 is a positive allosteric modulator and direct agonist of GABA A receptors. | ||
| M7158 | Pregnanolone | Others |
| Pregnanolone is a gABA A receptor positive allosteric modulator. | ||
| M7252 | SB 205384 | GABA Receptor |
| SB 205384 is a gABA A receptor modulator; slows current decay. | ||
| M7381 | TCS 1105 | Others |
| TCS 1105 is a gABA A α2 benzodiazepine receptor agonist. | ||
| M7382 | TCS 1205 | Others |
| TCS 1205 is a subtype-selective GABA A receptor agonist. | ||
| M7410 | THIP hydrochloride | GABA Receptor |
| Gaboxadol hydrochloride; Lu 02-030 HCl | ||
| THIP hydrochloride (Gaboxadol hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). | ||
| M7420 | TP 003 | Others |
| TP 003 is a functionally selective GABA A receptor (α3 subtype) partial agonist. | ||
| M7441 | U 90042 | Others |
| U 90042 is a gABA A receptor ligand. | ||
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