About 1 result found for searched term "G907 " (0.146 seconds)
Cat.No. | Name | Target |
---|---|---|
M29413 | G907 | Antibiotic |
G907 is a selective antagonist of ATP-binding cassette (ABC) transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. |
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