About 3 results found for searched term "FIIN-3" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8938 | FIIN-3 | FGFR |
| FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor with IC50 values of 13.1, 21, 31.4 and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. | ||
| M5127 | FIIN-2 | EGFR/HER2 |
| FIIN-2 is an irreversible, pan-FGFR inhibitor with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM for FGFR1/2/3/4, respectively. | ||
| M28061 | FIIN-1 | FGFR |
| FGFR irreversible inhibitor-1 | ||
| FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively. | ||
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