About 4 results found for searched term "FGFR1 inhibitor-9" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43504 | FGFR1 inhibitor-9 | FGFR |
| FGFR1 inhibitor-9 is an FGFR1 inhibitor (IC50s: 0.85 nM). | ||
| M1875 | PD173074 | FGFR |
| PD173074 is a selective FGFR1 and FGFR3 inhibitor with IC50 values of 5, 21.5, ~100, 17600 and 19800 nM for FGFR3, FGFR1, VEGFR2, PDGFR and c-Src respectively. | ||
| M3031 | SSR128129E | FGFR |
| SSR | ||
| SSR128129E is an orally-active and allosteric FGFR1 inhibitor with IC50 of 1.9 μM, while not affecting other related RTKs. | ||
| M28863 | PD-089828 | FGFR |
| PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity. | ||
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