FASN-IN-1 - Search Results | AbMole BioScience

About 6 results found for searched term "FASN-IN-1" (0.119 seconds)

Cat.No.	Name	Target
M14433	FASN-IN-1	FAS
	FASN-IN-1 is a fatty acid synthase (FASN) inhibitor.
M8622	TVB-3166	FAS
	TVB3166
	TVB-3166 is a cell-permeable pyrrazole derivative that inhibits cellular palmitate synthesis (IC₅₀ <100 nM) by fatty acid synthase (FASN) keto-reductase activity in a potent and reversible manner (IC₅₀ = 42 nM), effectively inhibiting palmitate-dependent survival of various cancer cells in cultures and xenografted tumor growth in mice vivo (60-100 mg/kg/d p.
M10175	TVB-3664	FAS
	TVB3664
	TVB-3664 is a FASN inhibitor with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression.
M14432	FASN-IN-4 tosylate	FAS
	FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.
M28252	GSK837149A	FAS
	GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer.
M56691	Fasnall	FAS
	Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM.