About 33 results found for searched term "Estrogen Receptor" (0.098 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43594 | Estrogen receptor antagonist 8 | Estrogen Receptor |
| Estrogen receptor antagonist 8 is a potent estrogen receptor ER antagonist with an EC50 of 4.160 μM. | ||
| M43595 | Estrogen receptor modulator 8 | Estrogen Receptor |
| Estrogen receptor modulator 8 is an orally active inhibitor of Estrogen Receptor/ERR α (IC50=0.437 nM, MCF-7 cells). | ||
| M43600 | Estrogen receptor modulator 7 | Estrogen Receptor |
| Estrogen receptor modulator 7 is a potent estrogen receptor modulator. | ||
| M1966 | Fulvestrant | Estrogen Receptor |
| ICI 182780; ZD 9238; ZM 182780 | ||
| Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. | ||
| M2097 | LY500307 | Estrogen Receptor |
| Erteberel | ||
| LY500307 is a potent, selective estrogen receptor beta agonist with an EC50 of 0.66 nM. | ||
| M2280 | Tamoxifen Citrate (ICI 46474) | Estrogen Receptor |
| ICI 46474; Istubal; Nolvadex | ||
| Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding. | ||
| M2437 | Bazedoxifene hydrochloride | Estrogen Receptor |
| TSE-424 | ||
| Bazedoxifene hydrochloride is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM. | ||
| M2516 | Cholesterol | Estrogen Receptor |
| Cholesterol is a major sterol in mammals, accounting for 20-25% of the structural components of the plasma membrane, and plays an important role in characterizing membrane fluidity and permeability, as well as the function of transporter and signaling proteins. In addition, Cholesterol is an endogenous estrogen-related receptor alpha (ERRα) agonist. | ||
| M2678 | Equol | Estrogen Receptor |
| (-)-(S)-Equol | ||
| Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. | ||
| M2683 | Estradiol Benzoate | Animal Modeling |
| β-estradiol-3-benzoate | ||
| Estradiol Benzoate is an estrogen analog and an estrogen receptor (ER) agonist that binds to human, murine, and chicken ERα with an IC50 in the range of 22-28 nM.In addition, Estradiol Benzoate can be used in animal disease models (e.g., rat bacterial vaginitis model, rat prostatitis model, etc.). Construct. | ||
| M2684 | Estradiol Cypionate | Estrogen Receptor |
| Depoestradiol | ||
| Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor. | ||
| M3251 | Bazedoxifene Acetate | Estrogen Receptor |
| TSE 424; WAY-TES 424 | ||
| Bazedoxifene Acetate is a third generation, oral and nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. | ||
| M3256 | Eplerenone | Others |
| Epoxymexrenone | ||
| Eplerenone (Epoxymexrenone) is a selective, competitive and oral aldosterone antagonist with an IC50 of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen, and glucocorticoid receptors. Eplerenone may be used in studies of hypertension and heart failure following myocardial infarction. | ||
| M3371 | Estriol | Estrogen Receptor |
| Oestriol | ||
| Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. | ||
| M3564 | Clomifene citrate | Estrogen Receptor |
| Clomifene citrate is a selective estrogen receptor modulator. | ||
| M3567 | Toremifene Citrate | Estrogen Receptor |
| FC 1157a; NK 622; Z-Toremifene Citrate | ||
| Toremifene Citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. | ||
| M3652 | Ospemifene | Estrogen Receptor |
| FC-1271a | ||
| Ospemifene is a non-hormonal selective estrogen receptor modulator (SERM) which is used for the treatment of dyspareunia. | ||
| M4008 | Liquiritigenin | Estrogen Receptor |
| 4',7-Dihydroxyflavanone | ||
| Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc. | ||
| M4368 | Kaempferol | Estrogen Receptor |
| Robigenin; Kempferol | ||
| Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. | ||
| M4374 | Gypenoside-XVII | Estrogen Receptor |
| Gynosaponin S | ||
| Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. | ||
| M4512 | Tectoridin | Estrogen Receptor |
| Tectoridin is an isoflavone isolated from Maackia Amurensis. Tectoridin is a phytoestrogen that activates estrogen and thyroid hormone receptors. Tectoridin exerts estrogenic effects through the ER dependent genomic pathway and the GPR30 dependent non-genomic pathway. | ||
| M4834 | Propyl pyrazole triol (PPT) | Estrogen Receptor |
| propyl pyrazole triol | ||
| PPT is a potent subtype-selective estrogen receptor agonist with EC50 ~ 200 pM and displays 410-fold selectivity for ERα over ERβ. | ||
| M4835 | DPN | Estrogen Receptor |
| Diarylpropionitrile | ||
| DPN is a highly potent estrogen ERβ receptor agonist with a 70-fold selectivity over ERα with EC50 values are 0.85 and 66 nM,respectively. | ||
| M5547 | Daidzein | PARP |
| Isoflavone | ||
| Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator. | ||
| M5668 | Bavachin | Estrogen Receptor |
| Corylifolin | ||
| Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively. | ||
| M5917 | Raloxifene HCl | Estrogen Receptor |
| LY156758 hydrochloride; Keoxifene HCl; LY139481 HCl | ||
| RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist. | ||
| M6083 | AZD9496 | Estrogen Receptor |
| AZD9496 is an oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models. | ||
| M6165 | GSK 4716 | Estrogen Receptor |
| GSK 4716 is a selective agonist with estrogen-related receptors ERRβ and ERRγ. | ||
| M6536 | BTC | Others |
| BTC is a selective estrogen receptor modulator (SERM). | ||
| M6640 | Cyclofenil | Others |
| Cyclofenil is a selective estrogen receptor modulator (SERM). | ||
| M6710 | Endoxifen Z-isomer hydrochloride | Estrogen Receptor |
| Endoxifen Z-isomer HCl | ||
| Endoxifen Z-isomer hydrochloride is a Tamoxifen metabolite and a potent estrogen receptor (ER) antagonist that concentration-dependently inhibits hERG with an IC50 value of 1.6 μM. | ||
| M6717 | ERB 041 | Estrogen Receptor |
| ERB-041; Prinaberel | ||
| ERB 041 is a potent and selective estrogen receptor β (ERβ) agonist, with IC50s of 5.4, 3.1, and 3.7 nM for ERβ in humans, rats, and mice, respectively.ERB 041 is more than 200 times more selective for ERβ than for ERα. In addition, ERB 041 inhibits the WNT/β-catenin signaling pathway and induces apoptosis in ovarian cancer cells. | ||
| M7353 | Tamoxifen | Estrogen Receptor |
| ICI47699; Z-Tamoxifen; trans-Tamoxifen | ||
| Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. | ||
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