About 12 results found for searched term "Epoxide Hydrolase" (0.15 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7421 | TPPU | Epoxide Hydrolase |
| TPPU is a potent soluble epoxide hydrolase inhibitor; orally bioavailable and brain penetrant. | ||
| M8247 | AUDA | Epoxide Hydrolase |
| AUDA is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β. | ||
| M10464 | EC5026 (BPN-19186) | Epoxide Hydrolase |
| BPN-19186 | ||
| EC5026 (BPN-19186) is a first-in-class, potent and orally active soluble inhibitor of Epoxide Hydrolase (sEH). EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators. | ||
| M14087 | Diflapolin | Epoxide Hydrolase |
| Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity. | ||
| M14423 | GSK2256294A | Epoxide Hydrolase |
| GSK 2256294 | ||
| GSK2256294A is a potent, reversible, tight binding inhibitor of isolated recombinant human sEH (soluble epoxide hydrolase) (IC50 = 27 pM; t1/2 = 121 min) and displays potent inhibition against the rat (IC50 = 61 pM) and murine (IC50 = 189 pM) orthologs of sEH. | ||
| M14424 | trans-AUCB | Epoxide Hydrolase |
| t-AUCB | ||
| trans-AUCB (t-AUCB) is a potent, orally active and selective soluble epoxide hydrolase (sEH) inhibitor with IC50s of 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively. trans-AUCB has anti-glioma activity. | ||
| M29566 | SWE101 | Epoxide Hydrolase |
| SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH. | ||
| M30487 | ARM1 | Aminopeptidase |
| 4BSA | ||
| ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC50 7.61 µM and epoxide hydrolase inhibitory activity with an IC50 12.4 µM. | ||
| M30879 | AR-9281 | Epoxide Hydrolase |
| APAU | ||
| AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (s-EH) inhibitor. AR-9281 can inhibits human sEH (HsEH) and murine sEH (MsEH) with IC50 values of 13.8 nM and 1.7 nM, respectively. AR9281 can be used for the research of inflammation, hypertension and type 2 diabetes. | ||
| M30945 | BI-1935 | Epoxide Hydrolase |
| BI-1935 is a potent soluble epoxide hydrolase (sEH) inhibitor. BI-1935 can be used for the research of cardiovascular disease. | ||
| M30959 | UC-1728 | Epoxide Hydrolase |
| t-TUCB | ||
| UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver. | ||
| M42392 | sEH inhibitor-16 | Epoxide Hydrolase |
| sEH inhibitor-16 is a soluble epoxide hydrolase (sEH) inhibitors with an IC50 of 2 nM. | ||
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