About 1 result found for searched term "Edicotinib" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10937 | Edicotinib | CSF-1R (c-Fms) |
| JNJ-40346527; JNJ-527 | ||
| Edicotinib (JNJ-40346527) is a potent, selective, blood-brain permeable and orally active CSF-1R inhibitor.IC50 3.2 nM. Edicotinib has less inhibitory effect on KIT and FLT3,IC50 The values are 20 nM and 190 nM, respectively. Edicotinib inhibits the expansion of microglia, weakens the proliferation of microglia and neurodegenerative degeneration. Edicotinib can be used in the study of Alzheimer's disease and rheumatoid arthritis. | ||
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