About 1 result found for searched term "ERAS-4001" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M66241 | ERAS-4001 | Ras |
| ERAS-4001 is a pan-KRAS inhibitor, it has potent antitumor activities and significantly inhibits the proliferation of wild-type and mutant (such as KRASG12D, KRASG12V and KRASG12C) cancer cells. ERAS-4001 binds to both wild-type KRAS and the KRAS G12X mutant, and inhibits downstream signalling by KRAS via effector proteins such as the RAF protein family. | ||
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