Dim16 - Search Results | AbMole BioScience

About 3 results found for searched term "Dim16" (0.27 seconds)

Cat.No.	Name	Target
M42609	Dim16	Serine/Threonine Protease
	Dim16 is a dual PCSK9/HMG-CoAR inhibitor, with an IC50 value of 19 nM for PCSK9.
M29255	BMS-1166 hydrochloride	PD-1/PD-L1
	BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
M58101	Recombinant Human EGFR Protein (CHO, C-His)	Cytokines and Growth Factors
	ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor
	EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling.