About 6 results found for searched term "DYRK" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6478 | AZ Dyrk1B 33 | Others |
| AZ Dyrk1B 33 is a potent and selective Dyrk1B kinase inhibitor. | ||
| M7390 | TC-S 7004 | Others |
| Dyrk1B/A-IN-1 | ||
| TC-S 7004 is a potent and selective DYRK1A/B inhibitor. | ||
| M28808 | Dyrk1A-IN-5 | DYRK |
| Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with an IC50 of 2.1 μM. Dyrk1A-IN-5 can be used for Down syndrome research. | ||
| M43337 | DYRKtide | Others |
| DYRKtide is a biological active peptide. | ||
| M57196 | Dyrk1A-IN-4 | DYRK |
| Dyrk1A-IN-4 is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. | ||
| M58573 | DYRK1-IN-1 | DYRK |
| DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. | ||
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