About 11 results found for searched term "Cyclosporin H" (0.12 seconds)
Cat.No. | Name | Target |
---|---|---|
M22091 | Cyclosporin H | Others |
Cyclosporin H | ||
M1831 | Cyclosporine A | Immunology/Inflammation |
Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1 | ||
Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. | ||
M1934 | Tacrolimus (FK506) | Autophagy |
Fujimycin; FR900506; Prograf | ||
Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. *The compound is unstable in solutions, freshly prepared is recommended | ||
M4345 | Barlerin | NF-κB |
8-O-Acetyl shanzhiside methyl ester | ||
Barlerin (8-O-acetyl Shanzhiside methyl ester) is a cyclosporin glucoside isolated from folk medicinal plants in Xizang, China. Barlerin (8-O-acetyl Shanzhiside methyl ester) inhibited NF-κB activity. | ||
M20393 | Cyclosporine | Phosphatase |
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. | ||
M30341 | Cyclosporin C | Antifungal |
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs=0.1-5 μg/ml). | ||
M30408 | Cyclosporin B | Peptides |
Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation. | ||
M30409 | Cyclosporin D | NFAT |
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc). | ||
M31399 | Rencofilstat | Cyclophilin |
RCF; CRV431 | ||
Rencofilstat (CRV431) is a cyclosporine derivative as well as an orally active cycloheximide (CYPA) inhibitor for studies related to non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma. | ||
M52553 | Cyclosporin A-Derivative 3 | Phosphatase |
Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition. | ||
M54329 | Cyclosporin A-Derivative 1 Free base | Others |
Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A. |
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