About 25 results found for searched term "Coumarin 2" (0.164 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6182 | 7ACC1 | Monocarboxylate Transporter (MCT) |
| DEAC; Coumarin D 1421; D 1421 | ||
| 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. | ||
| M11505 | 7-Amino-4-methylcoumarin | Serine/Threonine Protease |
| Coumarin 120; AMC | ||
| 7-amino-4-methylcoumarin (Coumarin 120) is used as a fluorescent probe for many serine proteases. Used for high performance liquid chromatographic labeling. | ||
| M11536 | Coumarin 2 | Others |
| 7-(Ethylamino)-4,6-dimethylcoumarin | ||
| 7-(ethylamino)-4,6-dimethylchromen-2-one | ||
| M3306 | Daphnetin | PKC |
| 7,8-Dihydroxycoumarin | ||
| Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities. | ||
| M4785 | Pteryxin | AChR/AChE |
| Pteryxin, coumarin in the leaves of Pteryxin, has anti-obesity effect. Pteryxin is an effective butyrylcholinesterase (BChE) inhibitor with IC50 value of 12.96 μg/ mL | ||
| M7711 | Cloricromene | Others |
| Antithrombotic coumarin derivative that inhibits platelet and leukocyte function and suppresses arachidonic acid liberation by interfering with PLA2 activation. | ||
| M8657 | Sparstolonin B | TLR |
| Sparstolonin B (SsnB), an isocoumarin isolated from Sparganium stoloniferum and Scirpus yagara, is a potent TLR2 and TLR4 antagonist that exhibits anti-inflammatory and anti-viral (anti-HIV) properties. | ||
| M9360 | Dicoumarol | PDK1 |
| Dicoumarin; Dicumarol | ||
| Dicoumarol (Dicoumarin) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively. | ||
| M14674 | Coumarin-3-carboxylic Acid | Others |
| 2-Oxochromene-3-carboxylic acid | ||
| Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. | ||
| M16308 | Chalepensin | Cytochrome P450 (e.g. CYP17) |
| Chalepensin, a furanocoumarin isolated from the rutaceae plant Ruta chalepensis L., is a selective CYP2A6 inhibitor. Chalepensin also inhibits human CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4. | ||
| M19317 | Angelol B | Others |
| Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model. | ||
| M19370 | Marmesin | COX |
| S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity. | ||
| M38725 | Anisocoumarin H | Antifungal |
| Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL. | ||
| M39055 | 7-Ethoxy-4-methylcoumarin | Cytochrome P450 (e.g. CYP17) |
| 7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6. | ||
| M39058 | Licopyranocoumarin | Cytochrome P450 (e.g. CYP17) |
| Licopyranocoumarin is an isoflavonoid that shows CYP3A4 inhibitory activity with an IC50 of 32 μM. Licopyranocoumarin has potent neuroprotective activities. | ||
| M39059 | Isoglycycoumarin | Cytochrome P450 (e.g. CYP17) |
| Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6). | ||
| M39206 | Peucedanocoumarin III | Others |
| Peucedanocoumarin III is an inhibitor of (alpha)-synuclein and Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins. | ||
| M40115 | Angelol A | Others |
| Angelol A is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model. | ||
| M40121 | Cnidicin | Others |
| Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells. | ||
| M40440 | Angelol G | Others |
| Angelol G, a coumarin, can be isolated from Campylotropis hirtella. Angelol G shows inhibitory activity for prostate specific antigen (PSA)IC50 value of 152.1μM. Angelol G can be used for the research of benign prostate hyperplasia (BPH). | ||
| M41459 | DNA polymerase-IN-2 | DNA/RNA Synthesis |
| DNA polymerase-IN-2, a coumarin derivative, exhibits inhibitory activity against Taq DNA polymerase with IC50 of 48.25 μM , which can be used in value-added disease research. | ||
| M42499 | MTHFD2-IN-4 sodium | Dehydrogenase |
| MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. | ||
| M42500 | MTHFD2-IN-4 | Dehydrogenase |
| MTHFD2-IN-4, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. | ||
| M42935 | DNA polymerase-IN-4 | Others |
| DNA polymerase-IN-4, a coumarin derivative, has antiretroviral activity with IC50 value of 134.22 μM. | ||
| M54290 | Mca-SEVNLDAEFK(Dnp)-NH2 | Fluorescent Dye |
| Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. | ||
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