About 2 results found for searched term "Carfilzomib" (0.223 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2152 | Carfilzomib | Proteasome |
| PR-171 | ||
| Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of <5 nM. Carfilzomib irreverently selectively binds to the active site containing n-terminal threonine of the 20S proteasome and proteolytic core particles of the 26S proteasome.*The compound is unstable in solutions, freshly prepared is recommended. | ||
| M29292 | WRR139 | Others |
| WRR139 is a peptide vinyl sulfone involving in disease processes such as inflammation and cancer. WRR139 is also a cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1 inhibitor. WRR139 enhances Carfilzomib cytotoxicity against cancer cells. | ||
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