About 30 results found for searched term "Carbonic Anhydrase" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M15015 | Recombinant Human Carbonic Anhydrase 1/CA1 (E.coli,C-6His) | Cytokines and Growth Factors |
| Carbonate Dehydratase I; Carbonic Anhydrase B | ||
| The recombinant human Carbonic Anhydrase 1/CA1 protein was produced by our escherichia coli expression system, and the target gene encoding ALA2-PHE261 was expressed at the C-terminal as 6His marker. Accession # : P00915. | ||
| M42296 | Carbonic anhydrase inhibitor 15 | Carbonic Anhydrase |
| Carbonic anhydrase inhibitor 15 is a carbonic anhydrase inhibitor (Ki: 8.5 nM for hCA II). | ||
| M2469 | Brinzolamide | Carbonic Anhydrase |
| AL-4862 | ||
| Brinzolamide (Brinzolamide) is a potent and effective carbonic anhydrase-II inhibitor with an IC50 of 3.19 nM.In addition, Brinzolamide reduces intraocular aqueous humor production in the eye and may be used in studies related to glaucoma. | ||
| M2690 | Ethoxzolamide | Carbonic Anhydrase |
| Redupresin; L-643786; PNU-4191 | ||
| Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively. | ||
| M2709 | Fluorometholone Acetate | Carbonic Anhydrase |
| Fluorometholone Acetate is a synthetic corticosteroid and a potent carbonic anhydrase (CA) inhibitor with IC50s of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It has anti-inflammatory activity and may be used in studies related to steroid-responsive ocular inflammation. | ||
| M2840 | Methazolamide | Carbonic Anhydrase |
| L584601 | ||
| Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. | ||
| M3099 | U-104 | Carbonic Anhydrase |
| MST-104; SLC-0111 | ||
| U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. | ||
| M3305 | Tioxolone | Carbonic Anhydrase |
| Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. | ||
| M3421 | Dichlorphenamide | Carbonic Anhydrase |
| Diclofenamide | ||
| Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. | ||
| M3856 | Acetazolamide | Carbonic Anhydrase |
| Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM. | ||
| M4398 | Dimethylfraxetin | Others |
| Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a Ki value of 0.0097 μM. | ||
| M5591 | Dorzolamide HCl | Carbonic Anhydrase |
| MK-507 (L-671152) HCl | ||
| Dorzolamide HCl is a water-soluble inhibitor of human carbonic anhydrase carbonic anhydrase II and IV with a Ki of 1.9 nM and 31 nM, respectively, and can be used in glaucoma-related studies. | ||
| M8357 | Dorzolamide | Carbonic Anhydrase |
| L671152; MK507 | ||
| Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0. | ||
| M8477 | Indisulam | PROTAC |
| E 7070 | ||
| Indisulam is a carbonic anhydrase inibitor and antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition. | ||
| M10307 | Benzolamide | Others |
| CL-11366; W-1803 | ||
| Benzolamide is a carbonic anhydrase inhibitor. | ||
| M19874 | Mafenide hydrochloride | Antibiotic |
| 4-Aminomethylbenzenesulfonamide hydrochloride | ||
| Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. | ||
| M20427 | Benzenesulfonamide | Carbonic Anhydrase |
| Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide | ||
| Benzenesulfonamide ia an inhibitor of carbonic anhydrases. | ||
| M20508 | Sulfamide | Others |
| Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay | ||
| M21500 | Polmacoxib | COX |
| CG100649 | ||
| Polmacoxib (CG100649) is a first-in-class, orally active non-steroidal anti-inflammatory compound (NSAID) that acts as a dual inhibitor. It inhibited COX-2 (IC50 ~ 0.1 μg/ml) and carbonic anhydrase. | ||
| M25289 | Girentuximab | Carbonic Anhydrase |
| G250; cG250 | ||
| Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). | ||
| M30374 | Sultiame | Carbonic Anhydrase |
| Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent. | ||
| M39054 | hCAI/II-IN-6 | Carbonic Anhydrase |
| hCAI/II-IN-6 is an orally active human carbonic anhydrase (CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms with Ki values of 220, 4.9, 6.5 and ＞50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo. | ||
| M40659 | hA2A/hCA XII modulator 1 | Adenosine Receptor |
| hA2A/hCA XII modulator 1 is a triazolopyrazine and a potent adenosine receptor hA2A antagonist, with Ki of 6.4 nM, 4.819 μM, and >30 μM for hA2AAR, hA1AR, and hA3AR, respectively. hA2A/hCA XII modulator 1 is a potent inhibitor of human carbonic anhydrase XII (hCA XII). In addition, hA2A/hCA XII modulator 1 is also a potent human carbonic anhydrase XII (hCA XII) inhibitor with Ki of 6.2 nM, 46 nM, 466 nM, 8.351 μM for hCA XII, hCA II, hCA IX, and hCA I, respectively, and can be used in cancer-related studies. | ||
| M42293 | hCAIX-IN-18 | Carbonic Anhydrase |
| hCAIX-IN-18 is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. | ||
| M42295 | hCA/VEGFR-2-IN-1 | Carbonic Anhydrase |
| hCA/VEGFR-2-IN-1 is a potent dual Carbonic Anhydrase(CA) IX/XII with Ki values of 4.7 nM and 8.3 nM for hCA XII and hCA IX, respectively. | ||
| M42298 | CA inhibitor 2 | Carbonic Anhydrase |
| CA inhibitor 2 is a carbonic anhydrase inhibitor (IC50: 0.033 μM). | ||
| M42299 | WES-1 | Carbonic Anhydrase |
| WES-1 is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). | ||
| M49459 | Acetazolamide sodium | Carbonic Anhydrase |
| Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.Acetazolamide reduces the production of intraocular aqueous humor and may be used in glaucoma-related studies. | ||
| M56594 | Disulfamide | Carbonic Anhydrase |
| Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. | ||
| M56593 | Quinethazone | Carbonic Anhydrase |
| Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. | ||
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