About 12 results found for searched term "Calcium-sensing Receptor" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M6190 | Calcium-Sensing Receptor Antagonists I | Calcium-sensing Receptor |
Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. | ||
M6555 | Calhex 231 | Calcium-sensing Receptor |
Calhex 231 is a negative allosteric modulator of the calcium-sensing receptor. | ||
M6741 | Gadolinium chloride | TRP Channel |
Gadolinium chloride is a stretch-activated calcium channel blocker; calcium-sensing receptor agonist. | ||
M7181 | R 568 hydrochloride | Others |
R 568 hydrochloride is a positive allosteric modulator of the human calcium-sensing receptor. | ||
M8306 | NPS2143 hydrochloride | Others |
NPS2143 is a selective calcium-sensing receptor (CaR) antagonist. | ||
M21421 | Upacicalcet | Calcium-sensing Receptor |
Upacicalcet is a calcium-sensing receptor (CaSR) agonist being developed for the study of secondary hyperparathyroidism (SHPT). | ||
M28089 | Etelcalcetide | Calcium-sensing Receptor |
AMG 416; KAI-4169 | ||
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis. | ||
M29964 | SB-423557 | Calcium-sensing Receptor |
SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation. | ||
M29965 | SB-423562 | Calcium-sensing Receptor |
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research. | ||
M53232 | Gamma-Glu-Abu | Others |
Gamma-Glu-Abu is a potent calcium sensing receptor (CaSR) agonist. | ||
M56155 | Ronacaleret | Others |
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. | ||
M56154 | Ronacaleret hydrochloride | Others |
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. |
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