About 30 results found for searched term "Calcium Channel" (0.09 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2248 | Cilnidipine | Calcium Channel |
| FRC 8653 | ||
| Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. | ||
| M2425 | Azelnidipine | Calcium Channel |
| UR-12592; CS 905 | ||
| Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects. | ||
| M2820 | Lomerizine dihydrochloride | Calcium Channel |
| KB-2796 | ||
| Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine. | ||
| M2843 | Methyclothiazide | Carbonic Anhydrase |
| Methyclothiazide (MCTZ) is an orally active, substituted benzothiazide that also antagonizes extracellular voltage-dependent calcium channel (VDCC) activity. It can be used in the study of hypertension-related diseases. | ||
| M2881 | Nicardipine hydrochloride | Calcium Channel |
| YC-93 Hydrochloride | ||
| Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders. | ||
| M3118 | Verapamil hydrochloride | Calcium Channel |
| (±)-Verapamil hydrochlorid; CP-16533-1 hydrochloride | ||
| Verapamil hydrochloride (VPH) is an orally active L-type calcium channel inhibitor that eliminates calcium channel agonist-induced calcium inward flow and apoptosis. Verapamil hydrochloride is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. | ||
| M3181 | Nicaraven | Others |
| Nicaraven is a novel free radical scavenger, a calcium channel blocker. | ||
| M3210 | Benidipine hydrochloride | Calcium Channel |
| KW-3049 | ||
| Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. | ||
| M3296 | Manidipine dihydrochloride | Calcium Channel |
| CV-4093 | ||
| Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4. | ||
| M3418 | Bupivacaine hydrochloride | Animal experimental anesthetics |
| Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain. | ||
| M3440 | Nilvadipine | Calcium Channel |
| ARC029, FR34235 | ||
| Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. | ||
| M3455 | Nitrendipine | Calcium Channel |
| BAY-E-5009 | ||
| Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM. | ||
| M3462 | Nisoldipine | Calcium Channel |
| BAY-k 5552 | ||
| Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. | ||
| M3498 | Nimodipine | Calcium Channel |
| BAY-e 9736 | ||
| Nimodipine is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. | ||
| M3500 | Diltiazem hydrochloride | Calcium Channel |
| CRD-401 | ||
| Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases. | ||
| M3613 | NP118809 | Calcium Channel |
| 39-1B4, NP-118809 | ||
| NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels. | ||
| M3958 | Clevidipine butyrate | Calcium Channel |
| Cleviprex | ||
| Clevidipine butyrate is an ultrashort-acting intravenous dihydropyridine calcium-channel blocker which is used as an agent for the reduction of blood pressure. | ||
| M4160 | Soyasaponin-Be | Potassium Channel |
| Dehydrosoyasaponin I (Soyasaponin Be; Dhs-i, a triterpenoid glycoside, is a potent and reversible calcium-activated potassium (MAxi-K) channel activator. | ||
| M4514 | Tetrandrine | Calcium Channel |
| NSC-77037; S,S-(+)-Tetrandrine; d-Tetrandrine | ||
| Tetrandrine (NSC-77037; D-tetrandrine) is a diphenylisoquinoline alkaloid that inhibits voltage-gated calcium channels (ICa) and Ca2+ -activated potassium channels. | ||
| M4756 | Berbamine | NF-κB |
| Berbamine is a natural compound extracted from the traditional Chinese medicine Phellodendron amurense, which has anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker. | ||
| M4968 | Mitiglinide calcium hydrate | Potassium Channel |
| KAD-1229 calcium hydrate; S-21403 calcium hydrate | ||
| Miglinide calcium hydrate is a compound used to study type 2 diabetes mellitus. It is a highly selective KATP channel antagonist. | ||
| M4973 | BAPTA-AM | Potassium Channel |
| BAPTA-AM is a selective, membrane-permeable calcium chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively. | ||
| M5073 | (R)-(+)-BAY K 8644 | Calcium Channel |
| (R)-(+)-Bay-K-8644; R-4407; NI-105; (+)-BAY-K-8644; Bayk8644 | ||
| (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. | ||
| M5080 | Efonidipine hydrochloride | Calcium Channel |
| NZ-105 | ||
| Efonidipine Hcl is a dual T-type and L-type calcium channel blocker . | ||
| M5139 | Amlodipine | Calcium Channel |
| UK-48340 | ||
| Amlodipine is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. | ||
| M5411 | Amlodipine Besylate | Calcium Channel |
| Amlodipine benzenesulfonate | ||
| Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. | ||
| M5607 | Efonidipine hydrochloride monoethanolate | Calcium Channel |
| NZ-105 hydrochloride monoethanolate | ||
| Efonidipine(NZ-105) Hcl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB). | ||
| M5629 | Ethosuximide | Calcium Channel |
| Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker. | ||
| M5640 | Fendiline HCl | Calcium Channel |
| Fendiline is a nonselective calcium channel blocker. | ||
| M5654 | Flunarizine 2HCl | Calcium Channel |
| KW-3149, R14950 | ||
| Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM. Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. | ||
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